患有IgG4相关良性胆道狭窄的年轻症状女性患者:一个病例报告
Faisal Janahi1, Khalifa Yusuf1, Mohamed Alchalban2
1Internal Medicine, Bahrain Defence Force Hospital, Riffa, BHR.
Cureus
|July 28, 2025
概括
本案例研究突出了一个年轻的女性,患有胆道狭窄和免疫球蛋白G4 (IgG4) 水平升高,呈现出独特的无系统IgG4相关疾病特征. 患者需要广泛的治疗,强调了疾病.
科学领域:
- 胃肠道学和免疫学
- 胆道疾病 胆道疾病
- 自身免疫性疾病 自身免疫性疾病
背景情况:
- 胆管狭窄的特征是胆管狭窄,阻碍胆汁流动,并可能导致各种症状.
- 免疫球蛋白G4相关疾病 (IgG4-RD) 是一种影响多个器官的纤维炎症性疾病.
研究的目的:
- 报告一个年轻女性患有普通胆道狭窄和IgG4水平升高的独特病例.
- 探索IgG4相关疾病的异质性.
主要方法:
- 一个年轻的女性患有反复出现的腹痛的案例介绍.
- 诊断成像显示了常见的胆道狭窄.
- 实验室检测显示血IgG4水平升高.
- 用序列内镜逆行胆血管细胞造影 (ERCP) 和皮质类固醇治疗.
主要成果:
- 患者出现了腹部疼痛和普通胆道狭窄.
- 检测到血IgG4水平升高.
- 没有观察到IgG4相关疾病的系统特征.
- 患者需要ERCP和口服皮质类固醇来管理.
结论:
- 这一案例说明了年轻女性IgG4相关疾病的不寻常表现.
- 这些发现有助于理解IgG4相关疾病的多样化临床谱.
- 需要进一步研究IgG4相关疾病的异质性.
更多相关视频
相关概念视频
Chronic Bowel Disorders: Introduction
541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541
Esophageal Strictures-II: Clinical Features and Management
160
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
160
Gallbladder
924
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
924
Esophageal Strictures-I: Introduction
269
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
269
Endoscopic Procedures V: ERCP
924
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
924
Gastritis III: Clinical Manifestations and Management
481
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
481


