得国家人类抗生素消费 (2017-2021):一个描述性的横截面研究
Zongo R Frank Edgard1, Kadidjia Bakari Traoré2, Colette Ngabéré3
1Organisation Mondiale de la Santé, N'djamena, Chad.
Frontiers in antibiotics
|July 28, 2025
概括
在2017年至2021年期间,得的抗生素消费量显著增加,这可能解释了抗生素耐药性高率. 虽然大部分消费在"访问"组,但"观看"组的使用量正在上升.
科学领域:
- 药理学和公共卫生
- 传染病流行病学 传染病流行病学
背景情况:
- 撒哈拉以南非洲 (SSA) 面临显著的抗生素耐药性 (ABR),得呈现高抗菌素耐药性 (AMR) 率.
- 在ABR和抗生素消费 (ABC) 之间存在强烈的相关性,但最近对得的ABC缺乏研究.
研究的目的:
- 分析2017年至2021年得抗生素消费 (ABC) 的趋势.
- 用世界卫生组织 (WHO) 的获取,观察和储备 (AWaRe) 抗生素分类来评估ABC模式.
主要方法:
- 一项回顾性描述性研究,利用N'Djamena的抗生素进口和分销数据.
- 确定每日剂量 (DDD) 和平均相对变化 (MRC) 的计算,以量化抗生素使用.
- 观察到的ABC数据与世卫组织AWaRe指南的比较.
主要成果:
- 平均ABC为每人每年2.5剂,在2020年升至5.3剂.
- 阿莫西西林,安培西林和硫甲醇/trimethoprim是消费最多的抗生素.
- 观察到"观察"类别中的几种抗生素的使用增加,尽管90%的ABC属于"访问"组.
结论:
- 在2017-2021年期间,得的大量抗生素消费可能导致该国高的ABR率.
- "观察"组抗生素使用的上升趋势迫切需要在得所有医疗保健层面实施ABC监测系统.
关键词:
这是ABCABC的ABCABC.这就是ABR ABR.现在还在等待查德 查德 查德 查德哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈在MRC中,MRC是MRC.更多相关视频
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