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Updated: Sep 13, 2025

Dorsal Root Ganglia Isolation and Primary Culture to Study Neurotransmitter Release
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Dorsal Root Ganglia Isolation and Primary Culture to Study Neurotransmitter Release

Published on: October 6, 2018

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使用YO-PRO-1对无神经损伤 (SNI) 的老鼠的DRG中释放活动的研究

Yanping Gu1, Guangwen Li1, Li-Yen Mae Huang1

  • 1Neurobiology, University of Texas Medical Branch.

microPublication biology
|July 28, 2025
PubMed
概括

研究人员开发了一种新的方法,用于检测神经损伤后背部根腺 (DRG) 细胞膜透性的变化. 静脉注射YO-PRO-1染料揭示了大鼠受伤神经元和周围细胞的细胞吸收.

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Live Imaging of Dorsal Root Axons after Rhizotomy

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Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure09:34

Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure

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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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