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早期与常规口服养在胰腺除术后:一个前性观察性研究
Ajay Sharma1, Vinay Kumar Mahala1, Anand Nagar1
1Department of Surgical Gastroenterology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, India.
Euroasian journal of hepato-gastroenterology
|July 28, 2025
概括
在胰腺二管切除术 (PD) 后6小时开始早期口服养 (EOF),与传统养相比,显著缩短了恢复时间和住院时间. 这种手术后增强恢复方案对于PD患者来说是安全有效的.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 消化系统手术 消化系统手术
背景情况:
- 手术后增强恢复 (ERAS) 协议越来越多地被采用用于胰腺二切除术 (PD).
- 之前的ERAS研究启动了术后第一天的口服养.
- 这项研究旨在评估早在手术后6小时开始口服养的影响.
研究的目的:
- 评估胰腺管切除术后6小时开始口服食 (液体和软) 的可行性和安全性.
- 为了比较接受早期口服养 (EOF) 和常规口服养 (COF) 的患者之间的术后结果.
主要方法:
- 一个由26名患者组成的前景队列 (I组) 接受了EOF,从PD后6小时开始.
- 一个由40名患者组成的回顾性队列 (II组) 从术后第一天开始接受COF.
- 关键结果包括饮食进步的时间,鼻胃管切除,第一次便通道和住院时间.
主要成果:
- EOF组显示,开始液体饮食 (0天与1.5天),软饮食 (0天与3.8天) 和固体饮食 (3.1天与7.2天) 的时间显著缩短 (p < 0.001).
- 在EOF组中观察到较早的鼻胃管切除 (1.6天 vs 3.9天) 和降低的再插入率 (p < 0.001).
- EOF组的患者经历了较早的首次便 (3.7天 vs 5.9天) 和较早的静脉输液停止 (3.4天 vs 5.2天),导致较短的住院时间 (5.9天 vs 8.8天) (p < 0.007).
结论:
- 在胰腺双管切除术后6小时开始的早期口服养 (EOF) 是可行的和安全的.
- EOF显著加快术后恢复,包括饮食进展和胃肠功能.
- 这种方法可以减少住院时间,而不会增加并发症或死亡率.
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