微生物组进化的模型包括宿主资源供应
Yao Xiao1, Teng Li1, Allen Rodrigo1
1School of Biological Sciences, The University of Auckland, 3A Symonds St, Auckland 1010, New Zealand.
ISME communications
|July 28, 2025
概括
主体微生物群的相互作用涉及成本和收益. 当宿主将许多微生物转移给后代,并将很少的微生物释放到环境中时,资源供应进化,平衡微生物群管理成本和收益.
科学领域:
- 进化生物学 进化生物学
- 微生物组研究 微生物组研究
- 计算生物学 计算生物学
背景情况:
- 多细胞宿主及其相关的微生物群落 (微生物组) 参与互利互动.
- 主体可能会投入资源来调节和招募特定的微生物,从而产生可能影响健康的能量成本.
- 对微生物组管理成本与累计收益平衡的进化策略仍然不太了解.
研究的目的:
- 研究宿主如何进化,以平衡消耗微生物群管理资源的成本和收益.
- 确定在何种条件下为微生物组调节提供资源的发展.
主要方法:
- 扩展之前开发的基于代理的宿主微生物组进化的计算模型.
- 将资源配置流程纳入模型.
- 在不同的宿主微生物相互作用参数下模拟进化动态.
主要成果:
- 当宿主将高百分比的微生物转移给后代,并为环境贡献低百分比时,资源供应会演变.
- 当宿主将其微生物组的高百分比贡献给环境时,资源供应不会演变,因为微生物可以从环境来源获得.
- 宿主不太可能为有益的微生物提供资源,如果他们可以从环境中轻松获得它们.
结论:
- 在特定的传播和环境贡献场景下,为微生物群管理提供宿主资源是最受欢迎的.
- 微生物的环境获取可以减少宿主资源供应的选择性压力.
- 微生物群管理宿主策略的演变取决于直接提供和环境微生物可用性之间的相互作用.
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