审查中的AREDS2:倡导统一法规
David Beckers1, Florian Kretz1, Karen Glandorf1
1Augenheilkunde, Precise Vision Augenärzte, Rheine, Deutschland.
概括
许多用于治疗与年龄相关的黄斑变性 (AMD) 的非处方补充剂与AREDS2公式不匹配. 像维生素C,维生素E和这样的关键成分通常远低于推量.
科学领域:
- 眼科医生 眼科 眼科
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 与年龄相关的黄斑变性 (AMD) 是老年人视力丧失的主要原因.
- 遵循AREDS2配方的食补充剂被认为可以减缓中级AMD的进展.
研究的目的:
- 系统地比较非处方药 (OTC) AMD补充剂的成分成分与AREDS2公式.
- 量化营养含量与已确定的AREDS2参考值的偏差.
主要方法:
- 在德国提供AMD补充剂的市场分析.
- 声明的成分和剂量的比较与AREDS2研究的参考值.
主要成果:
- 大多数分析的补充剂显示出与AREDS2配方的显著偏差.
- 平均度较低:维生素C为52.3%,维生素E为61.2%,为40.1%.
- 很少有产品与AREDS2的成分和剂量完全匹配.
结论:
- 在商用基于AREDS2的AMD补充剂中存在实质性的差异.
- 需要标准化的标签和监管指导方针,以便更好地进行比较.
- 加强标准化将支持基于证据的AMD补充剂的临床使用.
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