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Updated: Sep 13, 2025

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与自身免疫相关的TNFAIP3的一个新型误解变异揭示了STAT1/mTOR通路的贡献

Judith Potjewijd1, Hans J P M Koenen2, Caspar I van der Made3

  • 1Department of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands.

Clinical and experimental immunology
|July 28, 2025
PubMed
概括

一种新的TNFAIP3基因变异导致A20哈普隆缺陷 (HA20),导致多自免疫. 这一发现扩大了HA20的扩展.

关键词:
A20 简单的不充分性在 NF-κBB 中.通过STAT1和mTOR的路径.在TNFAIP3中使用.多种自身免疫的多种免疫.

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