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空间转录学识别了SPARC作为间歇性肺部疾病的预后标记.

Takayuki Niitsu1,2, Toshiaki Kataoka3, Kiyoharu Fukushima1,2

  • 1Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.

The Journal of pathology
|July 28, 2025
PubMed
概括

空间转录学确定SPARC是跨间歇性肺部疾病 (ILDs) 的渐进性肺纤维化中的关键分子. 较高的SPARC水平表明无法分类的ILDs (uILDs) 的预后不佳,表明其作为预后标记物的潜力.

关键词:
这就是SPARC的目的.纤维化 纤维化间歇性肺部疾病 (ILDs) 是一种肺部疾病.单细胞RNA测序 (scRNA-seq) 是一种空间转录组学 (ST)不能分类的ILDs (uILDs) 是一种不可分类的ILDs.

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