饮食胆摄入量和慢性病:从NHANES2005年到2020年的证据
Qinke Lv1, Chun Yao2, Jian Zhong3
1The First Clinical Medical College, Graduate School of Guangxi University of Traditional Chinese Medicine, Nanning, China.
Journal of the American Nutrition Association
|July 28, 2025
概括
饮食中较高的胆摄入量与慢性病 (CKD) 的风险降低有关. 这种必不可少的营养素可能在预防和控制CKD进展方面发挥保护作用.
科学领域:
- 营养科学 营养科学
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 是一个重要的全球健康问题,患病率和死亡率很高.
- 饮食因素被认为对CKD的进展至关重要.
- 胆在CKD风险中的特定作用尚未得到充分确立,这是一个必需的营养素.
研究的目的:
- 调查饮食中胆摄入量与CKD患病率之间的关联.
- 探索胆摄入量与CKD风险之间的剂量反应关系.
主要方法:
- 利用了2005-2020年国家健康和营养检查调查 (NHANES) 的29094名参与者的数据.
- 通过两个24小时的饮食回忆来评估饮食胆摄入量.
- 使用加权二进制物流回归和受限立方线 (RCS) 分析来评估相关性.
主要成果:
- 饮食中较高的胆摄入量与CKD风险显著反转相关 (OR,0.85;95% CI,0.78-0.93).
- 胆摄入量最高四分之一的个体与最低四分之一 (OR,0.84;95% CI,0.72-0.98) 相比,CKD的风险明显较低.
- 限制性立方脊柱分析表明,胆摄入量与降低CKD风险之间存在线性关系.
结论:
- 研究结果表明,饮食中的胆对CKD有保护作用.
- 较高的胆消费可能有助于预防和治疗慢性病.
- 需要进一步的研究,包括纵向和分子研究,以证实这些发现.
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