"周末战士"运动模式可以预防MASLD和与常规运动相比的死亡率:国家队列研究
Shira Zelber-Sagi1,2, James M Paik1,3, Dana Ivancovsky-Wajcmen1
1The Global NASH Council, Washington, DC, USA.
概括
周末战士 (WW) 身体活动模式,每周1-2天从事中等到剧烈的活动,显著降低了代谢功能障碍相关的脂肪性肝病 (MASLD) 的患病率和死亡率. 这种模式为MASLD患者提供了与定期运动相比较的保护.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 代谢功能障碍相关的脂肪性肝病 (MASLD) 准则建议每周进行>150分钟的中度至强度体力活动 (MVPA).
- "周末战士" (WW) 身体活动模式的有效性,即将MVPA集中在1-2天内,而不是在整个星期中散布,对于MASLD管理仍然不清楚.
研究的目的:
- 评估WW活动模式与MASLD流行率之间的关联.
- 评估WW模式对MASLD患者的死亡率和动脉样硬化心血管疾病 (ASCVD) 风险的影响.
主要方法:
- 利用了来自国家健康和营养检查调查 (2003-2006) 的数据,与到2019年的死亡记录联系在一起.
- 根据加速仪测量的MVPA,将参与者分为WW,活跃和不活跃的群体.
- 使用美国脂肪肝指数 (US FLI) 定义的MASLD≥30与至少一个心脏代谢风险因素.
主要成果:
- 与不活跃组相比,WW和活跃组的MASLD概率都较低 (WW OR:0.36;活跃OR:0.47).
- 在MASLD患者中,WW模式与较低的全因死亡率 (HR:0.35) 和较低的高ASCVD风险几率 (OR:0.27) 相关.
- 与不活跃的个人相比,活跃组还显示出死亡率 (HR:0.48) 和ASCVD风险 (OR:0.39) 的好处.
结论:
- 周末战士的体育活动模式显示了对MASLD的保护作用.
- 这种集中活动模式在MASLD的流行率,死亡率和ASCVD风险方面提供了与定期,分散的运动相比较的好处.
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