在骨科手术患者中出现术后妄想的危险因素:系统性审查和元分析
Yanan Niu1, Qiang Wang2, Jin Lu1
1Department of Spinal Surgery, Affiliated Hospital of Hebei University, Baoding City, Hebei Province, China.
Annals of medicine
|July 28, 2025
概括
在整形外科手术中,术后妄想与晚年,男性性别,糖尿病和认知问题有关. 识别这些风险因素对于更好的患者结果和有针对性的干预措施至关重要.
科学领域:
- 整形外科手术 整形外科手术
- 老年病的医生 老年病的医生
- 神经科学是一个神经科学.
背景情况:
- 手术后痴呆症是骨科手术后经常发生的严重并发症,特别是在老年患者中.
- 识别风险因素对于预防和管理这种情况至关重要.
研究的目的:
- 系统地审查和分析与骨科手术患者术后妄想相关的风险因素.
- 为临床实践和未来研究提供基于证据的见解.
主要方法:
- 在多个数据库 (PubMed,Cochrane Library等) 中进行了全面的文献搜索. 在2024年10月之前.
- 包括的研究使用纽卡斯尔-太华尺度 (NOS) 进行了质量评估.
- 使用随机效应模型进行了元分析,以确定聚合风险比率 (RR) 和加权平均差异 (WMD).
主要成果:
- 分析了19项涉及4410名患者的研究.
- 确定了重要的风险因素:晚年 (WMD:3.30年),男性性别 (RR:1.12),糖尿病 (RR:1.76),以及手术前的认知功能障碍 (RR:1.98).
- 身体质量指数 (BMI) 与妄想风险没有显著关联.
结论:
- 高龄,男性性别,糖尿病和术前认知功能障碍是骨科手术中术后妄想的主要危险因素.
- 这些发现强调了妄想的多因素性质,以及需要进行彻底的手术前评估.
- 未来的研究应该旨在开发整合可修改和不可修改风险因素的预测模型.
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