双侧运动皮层通过半球间抑制力产生与力控制在同位数单手收缩中分别调节
Zhongfei Bai1,2, Feifei Zhu1, Jack Jiaqi Zhang3
1Department of Neurology and Neurological Rehabilitation, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, People's Republic of China.
Journal of neurophysiology
|July 28, 2025
概括
双侧运动皮质 (M1) 通过调节短间隔半球间抑制 (SIHI) 来帮助单手力力产生. 这种M1规则增强了力量的产生,并提高了持续收缩期间的精度,为康复提供了洞察力.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 人体生理学 人体生理学
背景情况:
- 在单手力产生中,异侧原发动皮质 (M1) 的作用已经确立,但它对短间隔半球间抑制 (SIHI) 动力学和力控制精度的确切影响仍在争论中.
- 了解这些机制对于阐明运动控制策略和潜在的治疗干预至关重要.
研究的目的:
- 系统地调查ipsilateral M1如何通过SIHI调节单人力力产生和精度.
- 为了检查在同位数收缩期间在力量产生和微调力控制中双边M1的双重作用.
主要方法:
- 实验1使用10Hz的跨磁刺激 (TMS) 来评估扰乱ipsilateral M1活动对20%和50%最大自发收缩 (MVC) 期间力量跟踪变异性的影响.
- 实验2采用双线圈TMS来量化SIHI在持续的同度收缩期间的动态,通过变化系数 (CV) 测量行为表现.
主要成果:
- 干扰ipsilateral M1活动显著增加了20%和50%的MVC的力量跟踪变化率 (CV),证实了它在力量产生中的促进作用.
- 持续的收缩导致减少ipsilateral-to-activeSIHI,而收缩期间持久的SIHI与两种测试的MVC水平的力控制精度正相关.
结论:
- 双边M1动态调节SIHI,以调节单边手力生产和精度.
- 这种双向调制突显了异位单手收缩中ipsilateral M1的双重作用,这对中风后康复策略有影响.
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