中年和老年中国患者的TyG指数和高血压之间的关联:CHALRS的数据
Jun Wang1, Chao Tang2, Zhijie Xie1
1Department of Neurosurgery, Master of Medicine, The First People's Hospital of Linping District, Hangzhou, Zhejiang Province, China.
PloS one
|July 28, 2025
概括
抗胰岛素的标志物TyG指数与中年和老年中国成年人的高血压风险有关. 这一发现有助于识别高风险患高血压和相关心血管问题的个人.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 甘油三糖指数 (TyG) 是一种已验证的胰岛素耐药性的指标.
- 胰岛素抵抗与心血管和脑血管疾病有关.
- 特别是在糖尿病人群中,TyG指数和高血压之间的关系需要进一步研究.
研究的目的:
- 调查TyG指数与高血压风险之间的关联.
- 在中年和老年中国人群中识别高风险的高血压患者.
主要方法:
- 来自2015年中国健康与退休长度研究 (CHARLS) 的数据分析.
- 根据TyG指数将种群分为分层动物.
- 用于评估TyG指数与高血压关系的物流回归和限制立方线 (RCS) 模型.
- 进行的子组分析,以评估基线特征的影响.
主要成果:
- 总共有9695名参与者被纳入;33.7%的人患有高血压.
- 提升的TyG指数与糖尿病,心脏病和中风的发病率增加相关.
- 在TyG指数和高血压之间观察到统计学上显著的非线性关联 (p < 0.001).
- 亚组分析表明,基线特征改变了TyG指数与高血压的相关性.
结论:
- 泰格指数显示,在研究的人群中,高血压风险与高血压风险有显著的正相关性.
- 这种关联可能有助于早期识别高血压风险的个体.
- 通过TyG指数进行改善的血压管理,有可能减少心血管和脑血管事件.
相关概念视频
Hypertension III: Clinical Manifestations and Diagnostic Studies
48
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
48
Hypertension I: Introduction
76
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
76
Hypertension II: Pathophysiology
79
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
79
Hypertension and Regulation of Blood Pressure
3.1K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.1K
Hypertension IV: Drug Therapy and Lifestyle Modifications
40
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
40
Factors affecting Blood pressure
4.9K
Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Physiological Factors:
4.9K


