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囊手术后伤口愈合延迟的危险因素:一个元分析研究的协议
Zubing Mei1,2, Peixin Du1, Ye Han1
1Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
本系统性审查综合了关于部囊手术后伤口愈合延迟 (DWH) 风险因素的证据. 识别这些因素可以改善患者的治疗结果,并降低医疗保健成本.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 伤口治愈研究研究 伤口治愈研究
- 证据综合 证据综合
背景情况:
- 伤口愈合延迟 (DWH) 是囊瘤手术后的常见并发症,增加了患者的发病率和医疗费用.
- 现有的关于DWH风险因素的研究是分散的,缺乏全面的综合来指导临床实践.
- 这项研究解决了需要对DWH风险因素在囊手术中的综合理解的需求.
研究的目的:
- 系统地识别和评估与部囊手术后延迟伤口愈合 (DWH) 相关的风险因素.
- 结合和分类关于DWH风险因素的现有证据,以告知临床实践.
- 为了提供一个全面的概述影响囊瘤手术结果的因素.
主要方法:
- 按照PRISMA-P指南进行系统审查和元分析.
- 在主要数据库 (PubMed,Embase,Cochrane,Web of Science) 和灰色文学中进行全面的文献搜索.
- 包括观察性研究 (队列,病例控制) 与数据提取和偏差风险评估 (纽卡斯尔-太华尺度).
主要成果:
- 主要结果包括确定风险因素的赔率比率 (OR) 或相对风险 (RR).
- 如果异质性 (I2 < 50%) 允许,元分析将汇集效应估计;否则,将执行叙事综合.
- 将进行子组分析和出版偏差评估.
结论:
- 这项研究将提供一个强大的综合DWH的风险因素在部囊手术后.
- 识别可修改的风险因素可以提高术前优化和术后护理,可能降低DWH率.
- 未来的研究应该标准化DWH的定义,并探索未充分研究的因素,如伤口护理和微生物群.
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