美国烧伤协会临床实践指南关于在烧伤护理中输血血液产品的指南
David Wallace1, Athina Lavrentieva2, Kathleen S Romanowski3
1Ross Tilley Burn Centre and Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
概括
本指南建议限制性红细胞 (RBC) 输血门 (血红蛋白≥7 g/dL) 对于成年烧伤患者,以减少输血而不会恶化结果. 它还建议使用粘弹性测试来指导外科手术期间输血的血液产品.
科学领域:
- 医学指导方针 医学指导方针
- 烧伤护理 烧伤护理
- 输血医学 输血医学
背景情况:
- 血液产品输血在急性烧伤的成年人中很常见.
- 目前的输血实践各不相同,需要基于证据的指导方针.
- 优化输血策略可以改善患者的治疗结果和资源利用.
研究的目的:
- 为医院住院的急性烧伤成年人输血血液产品的临床实践指南制定.
- 提供关于输血门和策略的基于证据的建议.
- 为了解决关于在烧伤护理中输血干预的关键问题.
主要方法:
- 使用PICO格式进行系统的文献搜索.
- 包含并对10篇相关文章进行批判性审查.
- 临床实践指导方针的开发由一个调查员小组.
主要成果:
- 强烈建议限制红细胞 (RBC) 输血门 (血红蛋白≥7 g/dL) 烧伤≥20%的总烧伤表面积 (TBSA).
- 与自由门 (血红蛋白≥10 g/dL) 相比,限制性门与输血减少和类似感染,停留时间和死亡结果有关.
- 对复合人体红色素和特兰胺酸的有条件建议的弱点建议;在外科手术期间推粘性弹性测试 (血栓收缩镜/旋转血栓收缩镜).
结论:
- 对于成年烧伤患者,建议采用限制性红细胞输血策略.
- 粘弹性测试可以指导外科手术期间输血产品的输血,以尽量减少整体输血量.
- 需要对接受外科切除的成年烧伤患者的特定输血比率进行进一步的研究.
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