对伴随性精神性厌食症和强迫症障碍的治疗有效性:系统性审查
Molly Fennig Steinhoff1, Madison Massmann2, Kirsten Gilbert3
1Department of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
International journal of psychiatry in clinical practice
|July 28, 2025
概括
对伴随性精神性厌食症 (AN) 和强迫症 (OCD) 的治疗可能会改善AN症状,但不能改善OCD症状. 需要进一步的研究,以开发有效的治疗方法,同时发生的AN和强迫症.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
背景情况:
- 神经性厌食症 (AN) 和强迫症 (OCD) 经常同时发生.
- 和强迫症的并发症与更差的预后和治疗结果有关.
- 了解并发性AN和强迫症的治疗疗效对于改善患者的治疗结果至关重要.
研究的目的:
- 进行首次关于非药物治疗对伴并发性AN和强迫症患者的疗效的系统审查.
- 综合当前关于这种特定患者群体治疗有效性的证据.
主要方法:
- 在2024年1月之前对主要数据库 (PubMed,PsycNet,Scopus,ProQuest,Google Scholar) 进行了系统审查.
- 采用了PRISMA方法,并且该研究已经预先注册 (PROSPERO CRD42024507762).
- 包括的研究涵盖了各种治疗类型,研究设计和护理水平.
主要成果:
- 非药物治疗显示出改善AN症状的趋势.
- 强迫症症状在经过检查的治疗方法下并没有持续改善.
- 大多数研究都集中在最初为AN开发的治疗方法上.
- 在包括的研究中,偏差风险各不相同.
结论:
- 目前的非药物治疗可能对AN有效,但对伴随性强迫症症状不有效.
- 需要更多的研究,专门针对并发性AN和强迫症,特别是在严重的强迫症患者中.
- 未来的研究应该探索跨诊断治疗,调整强迫症治疗的AN,并利用纵向设计来评估复发和缓解.
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