孕期肠道寄生虫和贫血:对怀孕结果的双重打击
Heba M Aboelela1, Waleed M Tawfik2, Ghada M Mahmoud3
1Medical Parasitology Department, Faculty of Medicine, Benha University, Qalyubiyya, Egypt.
Parasitology international
|July 28, 2025
概括
肠道寄生虫感染 (IPI) 显著增加妊娠性贫血 (GA) 和不良妊娠结果 (如流产和SGA) 的风险. 在孕妇中早期发现和治疗IPI对于改善孕产妇和胎儿健康至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 孕产妇健康 孕产妇健康
背景情况:
- 妊娠性贫血 (GA) 影响全球30%的孕妇.
- 肠道寄生虫感染 (IPI) 被怀疑是GA的贡献者,但其影响尚不清楚.
- 了解IPI,GA严重程度和怀孕结果之间的联系至关重要.
研究的目的:
- 为了确定IPI在孕妇中的患病率.
- 评估IPI,GA发病率和严重程度以及怀孕结果之间的关系.
- 为公共卫生策略提供信息,以便在怀孕期间管理IPI.
主要方法:
- 对238名孕妇的临床评估.
- 便样本分析用于IPI检测.
- 针对特定的寄生虫抗体的ELISA (抗菌,抗菌IgG).
- 血红蛋白度 (HBC) 测量在第一和第三季度.
- 记录了怀孕的结果.
主要成果:
- 到第三个三个月,GA发病率从30.25%增加到50.84%.
- 45%的女性患有IPI,共感染率为43%.
- 阿斯卡里斯 lumbricoides (33.6%) 和Ancylostoma duodenale (19.6%) 是常见的.
- 在贫血妇女中,安基洛斯托马双瘤和斯基斯托索马感染的比例更高.
- 贫血妇女的妊娠并发症,流产和SGA的发生率明显更高.
结论:
- 孕期IPI会加剧母亲的贫血,并对妊娠结果产生负面影响.
- 寄生共感染是严重贫血,流产和SGA的高风险因素.
- 在怀孕前或怀孕初期进行常规的寄生虫学查对于减轻不良结果至关重要.
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