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一个ALE元分析纤维肌痛的疼痛处理变化:向一个基于证据的过程模型

Marco Cavicchioli1, Alberto Caruso2, Andrea Scalabrini3

  • 1Department of Dynamic and Clinical Psychology, and Health Studies, Faculty of Medicine and Psychology SAPIENZA University of Rome, Rome, Italy; Faculty of Psychology, Sigmund Freud University, Milan, Italy.

Neuroscience and biobehavioral reviews
|July 28, 2025
PubMed
概括

纤维肌痛 (FM) 患者表现出大脑对疼痛的反应发生变化,疼痛处理关键区域的活性增加,如背部前带皮层 (dACC). 这表明FM患者的疼痛敏感性和警性增加.

关键词:
纤维肌痛是一种纤维肌痛.疼痛矩阵是一种疼痛矩阵.疼痛处理是疼痛的处理.取决于任务的fMRI.

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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