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Updated: Sep 13, 2025

Genome-wide Analysis using ChIP to Identify Isoform-specific Gene Targets
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Published on: July 7, 2010

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白血病突变蛋白PHF6和PHIP形成一个染色素复合体,抑制急性髓性白血病的干性

Aishwarya S Pawar1,2, Patrick Somers1, Aleena Alex1

  • 1Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Genes & development
|July 28, 2025
PubMed
概括

PHF6和PHIP蛋白质的突变与急性髓性白血病 (AML) 有关. 这项研究揭示PHF6和PHIP形成了一个抑制白血病干的复合体,提供了新的治疗点.

关键词:
在这种情况下,染色染色素这种白血病是白血病.骨髓化物 骨髓化物树干性 树干性

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