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Updated: Sep 13, 2025

Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle
10:05

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Published on: March 5, 2019

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在细胞应激条件下,RSK1的非法定激活诱导EphA2-介导的细胞迁移

Yue Zhou1, Fang Zhang1, Akihiro Tanaka1

  • 1Department of Cancer Cell Biology, Faculty of Pharmaceutical Sciences, University of Toyama, Toyama, Toyama 930-0194, Japan.

Biological & pharmaceutical bulletin
|July 28, 2025
PubMed
概括

一个新的途径激活p90核糖体S6激酶1 (RSK1) 通过3-氨基酸依赖激酶1 (PDK1) 和基因激活蛋白激酶激活蛋白激酶2 (MK2). 这种PDK1-MK2-RSK1-EphA2轴驱动质母细胞细胞迁移,为癌症恶性提供了新的见解.

关键词:
细胞迁移 细胞迁移氨酸受体A2是什么基因激活蛋白酶激活蛋白质激酶2激活蛋白质激酶2p90 核糖体 S6 激酶 1 1 的作用.

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