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Updated: Sep 13, 2025

Author Spotlight: A Selective Luciferase-Based Assay for Monitoring ATG4B 27 Activity in Cells
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Published on: June 30, 2023

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铜,一个复合铜ATG4B和自抑制剂,表现出强大的抗癌作用

Peng-Fei Qiang1,2, Yao Wang2, Dong-Yang Zhang1

  • 1Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.

Acta pharmacologica Sinica
|July 28, 2025
PubMed
概括

铜 (CuPT) 有效抑制ATG4B蛋白酶活性,阻断自. 这种新型的铜复合体在体外和体内表现出强大的抗癌作用,诱导一种称为cuproptosis的新细胞死亡途径.

关键词:
在ATG4B中,它是ATG4B.这是一种抗癌药物.抑制自细胞的抑制.铜氨酸 (CuPT) 是一种铜氨酸.这就是cuproptosis.

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