基因序列数据治理和数据库工程的LISTEN原则
Colin J Carlson1, Monica Granados2, Alexandra Phelan3
1Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA. colin.carlson@yale.edu.
Nature genetics
|July 28, 2025
概括
对遗传数据的访问和利益共享 (ABS) 义务可以与开放科学原则相兼容. 简单的数据库设计和治理原则,如LISTEN,确保在开放的科学数据库中实现ABS.
科学领域:
- 生物信息学是一种生物信息学.
- 开放科学是一个开放的科学.
- 法律信息学 法律信息学
背景情况:
- 国际法律协议要求对基因序列数据进行访问和利益共享 (ABS).
- 批评者认为,ABS与开放科学原则相冲突,并对开放数据库提出实施挑战.
研究的目的:
- 通过展示ABS与开放科学的兼容性来解决批评.
- 提出将ABS集成到开放科学数据库中的实际解决方案.
主要方法:
- 分析开放科学原则和ABS法律框架.
- 为数据库设计和治理制定六项原则清单 (LISTEN:授权,识别,监督,透明,强制执行,非排他性).
- 探索LISTEN原则和FAIR数据共享原则之间的协同作用.
主要成果:
- 对ABS与开放科学不兼容的批评源于误解.
- LISTEN 检查列表为在数据库中实现 ABS 提供了一个实用的框架.
- LISTEN原则可以补充现有的开放科学数据共享框架,如FAIR.
结论:
- 通过深思熟虑的数据库设计和治理,ABS机制可以有效地整合到开放科学中.
- 对于与ABS系统互动的平台,LISTEN原则提供了一个可扩展的解决方案.
- 这种方法使法律义务与开放科学数据共享的道德相协调.
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