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Updated: Sep 13, 2025

Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials
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Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

Published on: March 9, 2017

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用于生物医学应用的光诱导二进制相互作用工具的工程

Yi-Tsang Lee1, Lei Guo2,3, Tien-Hung Lan1

  • 1Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, TX, USA.

Nature communications
|July 28, 2025
PubMed
概括

研究人员开发了两种可光诱导的二进制相互作用工具 (PhoBIT) 用于光遗传控制. 这些系统能够精确操纵蛋白质相互作用和细胞功能,在癌症中具有潜在的治疗应用.

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An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions07:59

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

Published on: March 22, 2018

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Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling08:51

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling

Published on: June 25, 2015

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相关概念视频

Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
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