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针对老年人的多学科药物优化计划的长期结果,包括初级保健和医院团队
Camille Guerin1, Romain Leguillon2,3,4, Albane Cherel5
1Department of Pharmacy, University Hospital of Caen Normandie, 14000, Caen, France. camillejeanne.guerin@gmail.com.
European journal of clinical pharmacology
|July 28, 2025
概括
在一年的时间里,OPTIMEDOC计划成功地在老年人中实施了69%的药物优化建议. 这种多学科的方法增强了可持续的治疗优化,特别是在放弃处方时.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 年长的成年人面临药物优化和抑郁症的障碍.
- 2006年至2018年期间,与毒品有关的住院病例显著增加.
- 该OPTIMEDOC计划利用一个多学科的团队进行临床药物审查,以改善处方.
研究的目的:
- 评估治疗优化方案的长期实施情况,至少在干预后六个月.
- 记录经常被处方和新推出的药物及其长期实施率.
主要方法:
- 在大学医院进行观察性研究 (2022年4月至2024年4月).
- 包括来自OPTIMEDOC计划的患者.
- 主要结果:建议的长期实施率;次要结果:根据ATC2类对优化药物的描述.
主要成果:
- 在1580条建议中,有1017条 (69.0%) 在一年内成功实施了143名患者 (平均年龄为86.4岁) 的建议.
- 实施率:81.8%的描述,58.3%的介绍,70.5%的修改.
- 对抑郁症精神药物,精神分析药物和与酸相关的障碍药物的高实施率 (>75%). 疫苗引入的实施率很低 (41%).
结论:
- 该OPTIMEDOC计划是可持续治疗优化的有效策略,特别是老年人的抑郁症.
- 初级保健和医院团队之间的多学科合作促进了适当和可持续的处方.
- 参与社区药剂师可以进一步改善治疗建议的实施.
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