对预测临床结果的营养指数的评估在重症老年患者中:一项前性队列研究
Ugur Balaban1, Nadir Yalcin2, Esat Kivanc Kaya3
1Department of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Türkiye. eczugurbalaban@gmail.com.
严重病患者 (mNUTRIC) 评分中的修改营养风险是老年患者死亡率和长时间ICU停留的最强预测因素. 老年营养风险指数 (GNRI) 也显示出对死亡结果的显著预测价值.
科学领域:
- 关键护理医学 关键护理医学
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 营养不良常见于重症老年患者中,导致不良的临床结果.
- 评估营养状况对于预测这个脆弱人群的预后至关重要.
研究的目的:
- 为了评估四个营养指数的预后价值在危急疾病的老年患者.
- 为了确定mNUTRIC,GNRI,HALP和NLR对ICU结果的预测准确性.
主要方法:
- 对接受医疗ICU治疗的老年患者 (≥65岁) 进行前性队列研究.
- 评估用于预测28天死亡率,ICU死亡率和ICU停留时间 (LOS) 的营养指数 (mNUTRIC,GNRI,HALP,NLR).
- 使用多变量回归和ROC曲线分析.
主要成果:
- 该mNUTRIC得分独立预测了28天死亡率,ICU死亡率和长期ICU LOS,准确度很高 (AUC 0.864,0.858).
- GNRI显示出死亡率的良好预测性能,但不是一个独立的因素.
- 在HALP和NLR中,死亡率的预后价值有限.
结论:
- mNUTRIC评分是老年ICU患者的强大预后工具.
- 此外,GNRI还为死亡率提供了有价值的预测见解,有助于风险分层和临床决策.
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