65岁以下成年人骨质疏松性骨折没有先前的骨质疏松性骨折的迹象:呼吁重新评估查指南
Alireza Mirzaei1,2, Mozhdeh Zabihiyeganeh1, Pouria Tabrizian1
1Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
BMC musculoskeletal disorders
|July 29, 2025
概括
许多年轻的骨质疏松症患者错过了骨密度测试标准,导致诊断不足. 目前的指导方针可能需要修订,以识别更有风险的个体并预防脆弱性骨折.
科学领域:
- 老年医学 老年医学
- 整形外科 整形外科 整形外科
- 内分泌学 在内分泌学.
背景情况:
- 骨质疏松症往往被诊断不足和治疗不足,特别是在65岁以下的人群中.
- 有效的干预措施存在,但在年轻人群中未得到充分利用.
- 骨折联络服务 (FLS) 旨在管理患有脆弱性骨折的患者.
研究的目的:
- 评估65岁以下患者骨质疏松性骨折的频率,并将其转移到FLS.
- 评估当前骨矿物质密度 (BMD) 测试指南在这个人口群体中的适用性.
- 识别骨质疏松症查和诊断中的差距.
主要方法:
- 来自FLS诊所的1,248名患者个人资料的回顾性审查 (2022年4月 - 2024年3月).
- 确定65岁以下患者中不符合通常的BMD查标准的比例.
- 分析了那些不符合评估骨质疏松症诊断率标准的人的骨质疏松症结果.
主要成果:
- 61.9%的分析患者 (772) 年龄在65岁以下.
- 在65岁以下的患者中,只有34%的人符合国际临床密度测量学会 (ISCD) 关于骨质疏松测试的指导方针.
- 在这组人群中,进行骨质检测的常见原因包括40岁后的脆弱性骨折 (18.4%),吸烟 (22.4%) 和与骨损失相关的疾病 (18%).
结论:
- 许多65岁以下的患有脆弱性骨折的患者不符合当前的BMD测试标准.
- 查中的这一差距可能导致未被识别的骨质疏松症和进一步的骨折.
- 对骨质疏松症查指南的修订对于识别有风险的个体和减少脆弱性骨折的负担至关重要.
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