相关实验视频
Updated: Sep 13, 2025

11:19
Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
11.6K
一种改进的生物陶密封剂,具有双重抗菌机制
Bashayer Baras1, Amal Almohaimede2, Yara Alshibani3
1Department of Restorative Dental Science, College of Dentistry, King Saud University, Riyadh 11432, Saudi Arabia.
Bioengineering (Basel, Switzerland)
|July 29, 2025
概括
添加银纳米粒子 (NAg) 和二甲基胺甲基酸盐 (DMAHDM) 给根管密封剂显著增强了它们对Enterococcus faecalis生物膜的抗菌作用. 这种组合保持了可接受的内牙应用的物理特性.
科学领域:
- 生物材料科学 生物材料科学
- 微生物学 微生物学
- 牙周内科医院 牙周内科医院 牙周内科医院
背景情况:
- 根管密封剂对于内牙成功至关重要.
- 提高密封剂的抗菌性质是一个正在进行的研究领域.
- Enterococcus faecalis 是一个常见的病原体在持续的内牙感染.
研究的目的:
- 为了评估银纳米颗粒 (NAg) 和二甲基胺六甲基甲酸盐 (DMAHDM) 在EndoSequence生物陶 (BC) 密封器中的抗菌功效.
- 评估这些添加剂对密封器物理性质的影响.
- 为了研究抗菌膜对Enterococcus faecalis.alis的活性.
主要方法:
- 准备了四组密封器:对照组,NAg修改组,DMAHDM修改组和组合NAg和DMAHDM修改组.
- 物理性能 (流动性,薄膜厚度) 根据ISO标准进行了测试.
- 通过测量殖民地形成单位 (CFU) 数量来评估抗菌活性,对牙盘上的Enterococcus faecalis生物膜进行评估.
主要成果:
- 所有经过测试的密封剂配方都符合ISO对流动性和薄膜厚度的要求.
- 0.15%的NAg和5%的DMAHDM的组合显著减少了Enterococcus faecalis CFU的数量,约为5个日志.
- 单个添加剂也显示了CFU计数的一些减少,但组合是最有效的.
结论:
- 银纳米粒子和DMAHDM的组合为开发先进的内密封剂提供了一个有前途的战略.
- 这些增强的密封剂具有强大的抗微生物特性,可以对抗Enterococcus faecalis生物膜.
- 测试度保持了临床应用所必需的可接受的物理特性.
更多相关视频
相关概念视频
Biofilms
278
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
278
Bacterial Signaling
34.2K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
34.2K
Surface Membrane Barriers
1.5K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.5K
Waterproofing and Anti-Bacterial Admixtures in Concrete
112
Concrete's susceptibility to water absorption is due to the capillary action within the pores of its hydrated cement paste. This action draws water in, creating the need for waterproofing admixtures to prevent such penetration. The efficacy of these admixtures is contingent upon the water pressure, with variations arising from different conditions such as rain, capillary rise, or hydrostatic pressure in structures intended to hold water.
Waterproofing admixtures render concrete hydrophobic,...
Waterproofing admixtures render concrete hydrophobic,...
112

