长期COVID患者的心血管表现
Gordana Krljanac1,2, Milika Asanin1,2, Mihajlo Viduljevic1
1Clinic of Cardiology, University Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Diagnostics (Basel, Switzerland)
|July 29, 2025
概括
长期COVID经常导致心脏问题,包括由炎症驱动的结构和功能变化. 多模式成像有助于检测这些心血管问题,以便及时治疗.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 医疗成像医学成像
背景情况:
- 长期COVID是SARS-CoV-2感染后的疾病,呈现出持续的症状,影响各种器官系统.
- 心血管表现越来越被认为是长期COVID的显著后果.
- 了解心脏参与的潜在机制对于患者管理至关重要.
研究的目的:
- 研究长期COVID患者心脏结构和功能变化的机制.
- 为了确定与长期COVID相关的心血管表型.
- 评估多模式成像在表征心脏参与方面的实用性.
主要方法:
- 研究包括176名长期COVID症状超过12周的门诊患者.
- 进行心声扫描,以评估左心室喷射率 (LVEF) 和心肌应变 (纵向和周围).
- 心脏磁共振 (CMR) 成像,包括晚期加多增强 (LGE) 和T1/T2映射,用于评估心脏病理.
主要成果:
- 患有长期COVID和心血管症状的患者经历了更高的住院率和更长的停留时间.
- 显著的心声回声学发现包括减少的LVEF,受损的纵向和周围应变,以及改变的CS PSS.
- 在58.2%的患者中,CMR揭示了病理发现,其中LGE流行,本地T1升高和本地T2升高的映射.
结论:
- 长期COVID经常导致心血管结构和功能变化,主要是由于持续的炎症.
- 多模式成像对于识别机制,预测慢性心肌炎和早期心力衰竭等疾病至关重要.
- 在长期COVID中早期识别心血管表型对于有效和及时的治疗干预至关重要.
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