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症状在正常压力水脑的时间过程:一个系统的审查

Bekir Rovčanin^1,2, Ibrahim Omerhodžić^1,2, Adem Nuhović³

¹Department of Neurosurgery, Clinical Center University of Sarajevo, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina.

Diagnostics (Basel, Switzerland)

|July 29, 2025

概括

腹腔关节切换有效地治疗正常压力头症 (NPH). 然而,症状持续时间对NPH患者手术结果的影响尚不清楚,需要进一步研究.

科学领域:

神经学神经学
神经外科神经外科
老年病的医生老年病的医生

背景情况:

异常性正常压力水脑 (NPH) 是一种具有挑战性的老年病症,具有步态,认知和尿路症状.
腹腔皮管 (VP) 轮流是NPH的已知治疗方法.
症状持续时间对NPH中VP分流结果的影响尚未得到充分证实.

研究的目的:

系统地审查有关正常压力脑病 (NPH) 患者症状持续时间的文献.
为了评估手术前症状持续时间和手术后结果之间的关联,在NPH的VP转移后.

主要方法:

在PubMed,Scopus和Embase数据库中进行了系统的文献搜索.
包括的研究评估了成年NPH患者的VP转移的临床或放射性结果,报告了症状持续时间和至少一个月的随访.
由于异质性,临床结果被定性分析.

主要成果:

分析了24项涉及1169名NPH患者的研究 (平均年龄72.45岁,平均症状持续时间33.04个月).
大多数研究表明,在VP分流后,临床改善.
关于症状持续时间和结果之间的相关性的发现是不一致的;有些人建议更短的持续时间带来更好的结果,而另一些人发现没有明确的联系.

结论:

腹腔关节切换是正常压力头症的有效治疗方法.
目前关于手术前症状持续时间对NPH中VP转移结果的预测价值的证据是不确定的.
需要标准化诊断协议和前性研究来澄清症状持续时间的作用,并优化NPH管理中的手术时间.

关键词:

异常性正常压力脑水症.在术后的结果.预后因素预后因素症状持续时间症状持续时间腹腔上腺突变器的突变器.

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