针对截肢后疼痛管理的有针对性的干预疗法:综合性审查
Dunja Savicevic1, Jovana Grupkovic2, Uros Dabetic2,3
1Special Hospital for Rehabilitation and Orthopedic Prosthetics, 11000 Belgrade, Serbia.
Biomedicines
|July 29, 2025
概括
外围神经刺激等干预疗法为截肢后疼痛 (PAP) 提供了有希望的缓解,包括残余四肢疼痛和幻肢疼痛. 需要进一步的研究来优化这些治疗方法,以获得更好的长期结果.
科学领域:
- 疼痛管理 疼痛管理
- 神经学 神经学
- 再生医学是一种再生医学.
背景情况:
- 截肢后疼痛 (PAP),包括残余四肢疼痛 (RLP) 和幻肢疼痛 (PLP),显著影响生活质量.
- 目前的药理疗法往往对PAP提供不充分的缓解,强调了需要替代策略的需要.
研究的目的:
- 批判性地审查和综合目前用于PAP的干预疗法.
- 专注于这些干预措施的机制,临床有效性和实际应用.
主要方法:
- 在主要数据库 (PubMed,EMBASE,Scopus,Web of Science) 中对2015年至2025年间发表的研究进行了全面的文献搜索.
- 包括专注于外围神经干预和用于PAP管理的各种神经调节技术的文章.
主要成果:
- 外围干预 (酒精神经分解,RFA,CNL) 和神经调节 (SCS,DRG刺激,CES) 对PAP显示出有希望的结果.
- 周围神经刺激 (PNS) 证明了良好的安全性和有效性,可能防止疼痛慢性化.
结论:
- 当代干预疗法在PAP的多学科管理中是有价值的.
- 进一步的研究对于标准化算法,优化治疗决策和提高PAP患者的长期结果至关重要.
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