长期COVID及其影响:巴西的一项病例控制研究
Cristina M Ruas1,2, Maria Laura Silva2, Ana L G F Figueiredo3
1Social Pharmacy Department, Pharmacy Faculty, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Biomedicines
|July 29, 2025
概括
长期COVID显著影响认知和呼吸系统健康,大多数评估的症状在感染后恶化. 这项研究强调,需要在COVID-19后对个人进行持续监测,特别是在全球南方地区.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 长期COVID,或COVID-19后综合征,在SARS-CoV-2感染后长达两年的时间内表现出影响多个身体系统的持续症状.
- 了解不同人群中的症状患病率对于有效的长期管理至关重要.
研究的目的:
- 为了比较COVID-19感染前和感染后个体的症状患病率,与未感染的对照组进行比较.
- 为了调查COVID-19在巴西东南部的长期健康影响.
主要方法:
- 一项用虚拟问卷对巴西成年人进行的病例控制研究.
- 数据收集发生在2023年10月至2024年5月期间,包括来自MonitoraCovid计划的参与者.
- 分析包括2886名符合条件的个人,评估COVID-19感染前和后的症状流行率.
主要成果:
- 超过75%的参与者报告了之前的COVID-19阳性测试;大多数人都接种了疫苗.
- 感染COVID-19的个体报告感染后症状恶化,95.5%的评估条件受到影响,特别是认知和呼吸系统问题.
- 关键的COVID-19后症状包括记忆障碍,疲劳和呼吸短促;感染组中焦虑和睡眠障碍的发生率较低.
结论:
- 长期COVID显著影响认知健康,强调需要监测先前感染过的个体.
- 在全球南方的背景下进行进一步的研究对于充分了解COVID-19的长期后果至关重要.
- 调查结果强调了症状呈现的差异性以及需要特定环境的公共卫生策略.
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