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Updated: Sep 13, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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在癌症中准CDK4/6:分子对接和细胞毒性评价Thottea siliquosa根提取物

Maruthamuthu Rathinam Elakkiya1, Mohandas Krishnasreya1, Sureshkumar Tharani2

  • 1Department of Botany, PSGR Krishnammal College for Women, Coimbatore 641004, Tamil Nadu, India.

Biomedicines
|July 29, 2025
PubMed
概括

托特亚的根提取物显示出作为循环素依赖性激酶4和6 (CDK4/6) 的天然抑制剂的潜力. 这种植物性疗法可能为治疗CDK4/6-相关癌症提供更安全的替代方案.

关键词:
在ADME的个人资料上.它可以抑制CDK4/6的抑制.这是一片状的.细胞迁移 细胞迁移细胞毒性 细胞毒性分子对接的分子对接.

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Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts09:20

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