怀孕期间碳水化合物质量指数与代孕年龄较大的新生儿的风险之间的关联:来自BORN 2020研究的结果
Antigoni Tranidou1,2, Antonios Siargkas1,2, Ioannis Tsakiridis1
13rd Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Children (Basel, Switzerland)
|July 29, 2025
概括
怀孕早期消费低质量的碳水化合物会增加分娩大胎儿 (LGA) 婴儿的风险. 碳水化合物质量指数 (CQI) 显示了与LGA的复杂关联,突出了碳水化合物质量和数量在怀孕营养中的重要性.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 围产期流行病学 围产期流行病学
背景情况:
- 怀孕早期的饮食模式会影响胎儿的生长.
- 碳水化合物质量指数 (CQI) 是碳水化合物摄入质量的综合指标.
- 代孕年龄大 (LGA) 婴儿与日产期风险增加有关.
研究的目的:
- 调查怀孕早期碳水化合物质量 (CQI) 与LGA婴儿风险之间的关联.
- 在地中海群体中探索这种关联,包括怀孕期糖尿病 (GDM) 的妇女.
主要方法:
- 希腊的前性队列研究 (BORN 2020).
- 用经过验证的食物频率调查问卷评估的饮食摄入量.
- CQI是根据糖分指数,纤维密度,全颗粒与精制颗粒的比率以及固体与液体碳水化合物的比率来计算的.
- 用于分析LGA风险的多变量逻辑回归模型.
主要成果:
- 较高的低质量的碳水化合物摄入量与增加LGA风险有显著的关联 (aOR:4.25).
- 在一般人群中,中度的CQI显示出与增加LGA几率 (aOR ≈ 1.60) 的一致关联.
- 在GDM子组中,高CQI最初与LGA相关,但在完全调整后失去意义.
- 孕前母亲的BMI和身高在总人口和GDM亚组中分别与LGA有关.
结论:
- 怀孕早期摄入低质量的碳水化合物与增加LGA风险有关.
- CQI和LGA之间的关系是非线性的和不一致的,中度的CQI显示了显著的关联.
- 综合性饮食评估,考虑碳水化合物的质量和数量,对于怀孕营养指导至关重要,特别是对于高危人群.
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