相关实验视频
Updated: Sep 13, 2025
08:46
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
6.5K
在新生牛犊中被动免疫转移的失败:一个范围审查
Essam Abdelfattah1,2, Erik Fausak3, Gabriele Maier1
1Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Animals : an open access journal from MDPI
|July 29, 2025
概括
在牛犊中被动免疫转移 (FTPI) 的失败是一个重大问题,其患病率在5.8%至34.5%之间. 低活力小牛需要额外的注意力,以确保足够的胆乳摄入,以成功地传递被动免疫力.
科学领域:
- 兽医免疫学 兽医免疫学
- 新生儿小牛的健康状况
- 牛肉牛生产 牛肉牛生产
背景情况:
- 新生儿小牛有不成熟的免疫系统,依靠母乳母乳来传递被动免疫力.
- 被动免疫转移失败 (FTPI) 发生在小牛没有从母乳中获得足够的母体抗体 (IgG) 时.
- 牛犊FTPI的研究是最近的,牛犊运营缺乏确立的诊断和预防策略.
研究的目的:
- 进行范围审查,确定关于乳母乳管理最佳实践的出版文献.
- 确定最佳实践,以确保新生牛犊的被动免疫 (TPI) 适当转移.
- 综合当前关于FTPI诊断和预防在牛牛小牛系统的知识.
主要方法:
- 搜索了三个电子数据库 (CAB Direct,Scopus,PubMed) 的2003年至2025年的出版物.
- 选了800项初步研究,最终在全文审查和参考文献搜索后包含了63篇文章.
- 数据提取的重点是FTPI的乳酪管理,小牛和水相关的风险因素.
主要成果:
- 据估计,FTPI在牛犊中的流行率在5.8%至34.5%之间.
- 关键因素包括胆乳质量/数量,食时间/方法,小牛的活力,母体的身体状况和分娩困难.
- 对于牛犊的充足和最佳TPI,推的血清IgG水平分别为16g/L和24g/L.
- 对于TPI的现场诊断工具显示的结果是可变的,需要仔细解释.
结论:
- 活力较低,哺乳反射较弱的小牛具有FTPI的高风险,需要专注于乳母管理.
- 建议在牛肉小牛中建立足够的 (16 g/L) 和最佳 (24 g/L) 血清IgG水平的截止值.
- 需要进一步的研究来完善诊断准确性,并制定牛肉系统中FTPI的标准化预防策略.
相关概念视频
01:22Development of Immunocompetence
449
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
449
01:15Transcytosis of IgG
2.9K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.9K