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Updated: Sep 13, 2025

A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure
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氨酸限制差异调节大鼠大脑和肝脏的基切除修复途径中的基因表达

Ricardo Gredilla1, Monica Lopez-Torres2, Ines Sanchez-Roman2

  • 1Department of Physiology, Faculty of Medicine, Complutense University of Madrid (UCM), 28040 Madrid, Spain.

Biomolecules
|July 29, 2025
PubMed
概括

氨酸限制 (MetR) 通过提高DNA稳定性来延长寿命. 这项研究表明,MetR在大脑和肝脏中独特地改变基因切除修复 (BER) 基因表达,这表明基因组维护的组织特异性机制.

关键词:
修复DNA的修复DNA的修复老化的老化 衰老的老化结核酶 (endonuclease) 的作用是什么基因组稳定性的基因组稳定性葡萄糖糖酶是什么 葡萄糖糖酶是什么长寿 长寿是一个问题.氧化应激是一种氧化应激.

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