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Updated: Sep 13, 2025

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

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通过理性设计改善HMG-CoA减少酶从Ruegeria pomeroyi的辅因子性

Haizhao Xue1,2, Yanzhe Huang1,2, Aabid Manzoor Shah1

  • 1Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

Biomolecules
|July 29, 2025
PubMed
概括

研究人员设计了一种关键酶,3-基-3-甲基氨基-CoA减少酶 (HMGR),以利用NADH和NADPH. 这种双辅助因子HMGR突变因子通过提高酶灵活性和基质利用来增强化物生产.

关键词:
3-基-3-甲基格卢塔利尔-辅酶A减少酶双辅助因子特异性 双辅助因子特异性梅瓦诺酸的途径理性的设计理性的设计.

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