15

Ben Li1,2,3,4, Farah Shaikh1, Houssam Younes5

  • 1Division of Vascular Surgery, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1W8, Canada.

Biomolecules
|July 29, 2025
PubMed
概括

增长差异化因子15 (GDF15) 是外周动脉疾病 (PAD) 患者主要不良心血管事件 (MACE) 的强有力的预测因子. 这种应激反应性细胞因子,当与机器学习一起使用时,有助于识别高风险个体,以提供个性化的心血管护理.

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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