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估计的S100B摄入量与不同饮食中的微生物群生物多样性有关
Tehreema Ghaffar1, Veronica Volpini1, Serena Platania2
1Laboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.
Biomolecules
|July 29, 2025
概括
饮食中的S100B蛋白质摄入量与肠道微生物群多样性有积极的相关性. 较高的S100B饮食可能会降低克罗恩氏病的风险,这表明饮食S100B对健康的作用.
科学领域:
- 营养科学 营养科学
- 微生物组研究 微生物组研究
- 胃肠病学 胃肠病学
背景情况:
- 在神经系统中至关重要的S100B蛋白质存在于牛奶和农产品等常见食品中.
- 食S100B和肠道微生物群之间的潜在相互作用尚未得到充分了解.
- 这项研究调查了S100B摄入量与肠道微生物多样性之间的联系.
研究的目的:
- 在各种国际饮食模式中估计饮食中的S100B暴露.
- 分析饮食中的S100B水平与肠道微生物群生物多样性之间的关联.
- 探索饮食S100B在预防慢性疾病,特别是克罗恩病中的潜在作用.
主要方法:
- 在13个全球饮食模式中估计的S100B度.
- 从现有研究中使用香农指数评估微生物α多样性.
- 分析了与饮食模式和S100B水平有关的克罗恩病的相对风险.
主要成果:
- 在S100B度和微生物多样性 (香农指数) 之间观察到中度正相关性 (R2 = 0.537).
- 富含S100B的饮食,如地中海饮食,与更高的α-多样性有关.
- 低S100B的西方饮食显示克罗恩病的相对风险更高 (R2 = 0.780).
结论:
- 饮食中的S100B摄入量可能在调节肠道微生物群组成和多样性方面发挥重要作用.
- 较高的饮食S100B可能与克罗恩病等慢性炎症性疾病的风险降低有关.
- 这些发现强调了饮食S100B在人类健康中的流行病学和生态相关性.
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