腹腔外科手术诱导的口腔微生物组的潜在变化-一个范围审查
Zuzanna Ślebioda1, Hélène Rangé2,3,4, Marta Strózik-Wieczorek5
1Department of Periodontology and Oral Mucosa Diseases, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Antibiotics (Basel, Switzerland)
|July 29, 2025
概括
腹腔外科手术显著改变了口腔微生物组,增加了潜在的有害细菌,如Streptococcus mutans和Porphyromonas gingivalis. 患者需要在手术后进行仔细的牙科监测.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 胃肠病学 胃肠病学
背景情况:
- 肥胖与与正常体重个体相比,与明显的口腔微生物组特征有关.
- 手术干预,包括减肥手术 (BS),可以诱导显著的微生物学转变.
- 在BS之后口腔微生物组组成和负载的精确变化仍然不完全理解.
研究的目的:
- 审查目前关于腹手术后口腔微生物组变化的研究.
- 讨论这些转变对口腔健康的影响.
主要方法:
- 在PubMed/Medline,科学网和科克兰图书馆的系统文献搜索,截至2025年3月30日.
- 包括前性研究,分析患者的口腔微生物群变化后腹腔外科手术.
- 分析使用各种方法的研究:16S rRNA测序,PCR,培养和MALDI TOF MS.
主要成果:
- 八项研究在3-12个月的时间内检查了各种空腹手术 (袖子胃切除术,Roux-en-Y,Omega环,胃复合) 后的口腔微生物组变化.
- 一致的发现包括Streptococcus mutans的增加,Candida物种的增加,以及牙周炎相关细菌 (例如, Porphyromonas gingivalis) 的更高流行率.
- 一些研究表明,随着时间的推移,口腔微生物组的组成可能会转变为不太致病.
结论:
- 腹腔外科手术对口腔微生物平衡有深远的影响,无论是直接还是通过术后后果.
- 由于这些口腔微生物组的变化,接受减肥手术的患者需要保持警的牙科监测.
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