相关实验视频

Updated: Sep 13, 2025

Oral Biofilm Formation on Different Materials for Dental Implants

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

表面处理的商业纯 (CpTi) 用于人工唾液的牙植入物的抗菌行为在体外研究中

Roshni Bopanna¹, Neetha J Shetty¹, Ashith M Varadaraj²

¹Department of Periodontology, Manipal College of Dental Science Mangalore, Manipal Academy of Higher Education, Manipal 576 104, Karnataka, India.

Antibiotics (Basel, Switzerland)

|July 29, 2025

概括

和胺合的酸 (CeHAp和BiHAp) 涂层在植入物上显示出显著的抗菌活性,特别是在pH 6.5.5下对金黄色葡萄球菌有显著的抗菌活性. 这些发现表明植入物性能提高,感染风险降低.

科学领域:

生物材料科学生物材料科学
微生物学微生物学
表面化学表面化学

背景情况:

植入物需要表面修改,以增强骨质整合和微生物耐药性.
抗微生物涂层,如和胺合的酸 (CeHAp,BiHAp) 显示出改善植入物寿命和预防感染的希望.
目前的研究重点是评估这些化酸涂层在商业纯 (CpTi) 上的有效性.

研究的目的:

评估CpTi上的CeHAp和BiHAp涂层对常见的口腔微生物的抗菌活性.
为了比较这些涂料在不同pH值 (4.5,6.5,8) 的人工唾液中的有效性.
评估这些涂层在增强牙科植入物成功方面的潜力.

主要方法:

使用稀释方法测试了抗菌有效性对金黄色葡萄球菌,大肠杆菌和白 Candida.
被涂层的棒被化在注射的营养中,通过600nm的光密度测量微生物抑制.
统计分析包括Kruskal-Wallis ANOVA和Dwass-Steel-Critchlow-Fligner对对比的对比.

主要成果:

CeHAp和BiHAp涂层在pH值6.5.5时表现出对S. aureus (OD = 0.01) 的显著抗菌活性.
在pH 6.5 (p = 0.001) 时,抗菌活性对S. aureus比对大肠杆菌 (OD = 0.05) 更明显.
在pH 8 (p = 0.001) 时,对C. albicans (0.21) 观察到的抗菌活性最小.

结论:

在抑制微生物生长方面,BiHAp和CeHAp涂层的有效性取决于pH值.
这些涂层显示出增强植入物抗菌性能的潜力.
这些涂料的应用可能会导致牙科植入物结果的改善和更广泛的生物医学用途.

关键词:

这就是CPTI的意思.抗微生物活性的抗微生物活性.牙植入物是指牙植入物.添加了合剂的氧酸盐.表面涂料的表面涂料.

更多相关视频

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

Published on: March 14, 2025

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants

Published on: August 5, 2021

相关概念视频

Bacterial Signaling

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

Surface Membrane Barriers

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...