抗微生物耐药的葡萄球菌种类. 在意大利中部被 (Erinaceus europaeus) 住
Fabrizio Bertelloni1, Francesca Pauselli1, Giulia Cagnoli1
1Department of Veterinary Science, University of Pisa, Viale delle Piagge 2, 56124 Pisa, Italy.
Antibiotics (Basel, Switzerland)
|July 29, 2025
概括
欧洲刺携带抗菌素耐药的葡萄球菌,对其他动物和人类构成风险. 这些刺还可以表明它们的环境中存在耐药细菌.
科学领域:
- 兽医微生物学 兽医微生物学
- 动物传播疾病 动物传播疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 欧洲刺居住在人类居住的地区,呈现潜在的病原体传播途径.
- 了解刺在葡萄球菌感染流行病学中的作用对于公众和动物健康至关重要.
研究的目的:
- 调查欧洲刺中葡萄球菌物种的存在和特征.
- 确定在孤立的葡萄球菌菌株中抗微生物耐药性概况和毒素基因存在.
主要方法:
- 对18个欧洲刺尸体进行了Staphylococcus spp.的分析. 隔离. 隔离. 在隔离.
- 孤立菌株的类型化和查脱皮毒素基因 (eta,etb).
- 抗微生物耐药性的表型和基因型表征,包括特定的耐药性基因 (blaZ, mecA, vanA, vanB).
主要成果:
- 隔离了54种葡萄球菌菌株,包括金黄色菌和其他物种.
- 没有任何菌株含有脱皮毒素基因 (eta,etb).
- 抗微生物药物耐药性的高患病率:72.20%对至少一种抗微生物药物表现出耐药性,38.80%对多种抗微生物药物表现出耐药性. 值得注意的是,74.08%的人表现出对红红素的中级耐药性. 在37.93%的分离物体中观察到青素耐药性,与西林的一些共耐药性. 在3.70%的菌株中发现了万科米辛耐药性 (中级和耐药),但没有vanA或vanB基因. 在27.13%的青素耐药菌株中检测到MecA基因. 总体而言,3.70%的人具有广泛的耐药性 (XDR),16.66%的人具有多重耐药性 (MDR).
结论:
- 欧洲刺携带抗菌素耐药的葡萄球菌,作为传染给其他动物和人类的潜在储库.
- 刺可以作为有价值的生物指标来监测它们息地内的循环病原体和抗菌素耐药细菌.
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