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Updated: Jul 14, 2026

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
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微循环功能障碍的动力学在Paclitaxel在活体老鼠模型中的应用期间

Susanne Reuter1,2, Rika Bajorat3, Fabian Müller-Graf3

  • 1Institute for Experimental Surgery, University Medical Center Rostock, Schillingallee 69a, 18057 Rostock, Germany.

Journal of clinical medicine
|July 29, 2025
PubMed
概括

帕克利塔克塞尔化疗会引起即时和持久的微循环功能障碍,影响周围神经. 预防化疗诱导的外围神经病变的干预措施可能是最有效的,当早期开始并持续至少三小时.

关键词:
化疗诱导的周围神经病变 (CIPN)内皮损伤的内皮病变.这是一种炎症炎症炎症炎症.静脉内光显微镜的使用.微血管损伤的动力学

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Drugs that Stabilize Microtubules01:15

Drugs that Stabilize Microtubules

Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...