长期后COVID-19肺部后遗症的放射学和临床相关性
Gorkem Durak1, Kaan Akin2, Okan Cetin2
1Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL 60611, USA.
Journal of clinical medicine
|July 29, 2025
概括
长期的COVID-19肺炎可能会导致持续的肺部异常,纤维状变化很常见. 许多非纤维性变化随着时间的推移而改善,与疲劳和胸痛等症状相关.
科学领域:
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 在COVID-19肺炎后的长期肺部变化尚未完全理解.
- 持续的成像异常和长期的COVID症状之间的关系需要调查.
研究的目的:
- 调查COVID-19肺炎患者的成像异常在10个月内持续存在的情况.
- 为了将成像发现与临床症状和实验室数据相关联.
主要方法:
- 93名中度至严重的COVID-19肺炎患者进行了随访CT扫描.
- 放射科医生评估了肺部的参与和变化的持续性 (非纤维化和纤维化类型).
- 分析了临床和实验室数据,包括中期和长期变化的子队列.
主要成果:
- 在36.6%的患者中观察到持久的非纤维化变化,在75.3%的患者中观察到纤维化样变化.
- 与初始CT得分,LDH和费里水平相关的持久变化.
- 疲劳和胸痛在持续的非纤维状变化中更频繁;胸痛在纤维状变化中更频繁.
结论:
- 最初的CT和实验室发现可以预测COVID-19肺炎的长期后果.
- 非纤维化肺部变化通常会随着时间的推移而减弱.
- 持续的成像发现与长期的COVID临床结果相关.
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