在Omicron阶段感染的长期COVID患者的症状趋势和恢复时间
Hiroshi Akiyama1, Yasue Sakurada1, Hiroyuki Honda1
1Department of General Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kitaku, Okayama 700-8558, Japan.
长时间的COVID恢复有所不同,更多的女性经历了持续的症状. 症状数量和性别显著影响长期COVID持续时间和严重程度.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 内部医学 内部医学
背景情况:
- 长期COVID的病理生理学仍然不清楚,需要基于症状的管理.
- 在COVID-19感染后的持续症状可能持续数月,持续时间不可预测.
- 了解影响长期COVID持续性的因素对于患者护理至关重要.
研究的目的:
- 调查早期和持续长期COVID病例之间的临床差异.
- 为了确定COVID-19感染后长期症状持续时间的预测因素.
- 为了探索长期COVID患者的性别特征.
主要方法:
- 对774名长期COVID症状患者的回顾性分析.
- 根据症状持续时间 (>180天) 将其分为早期恢复 (ER) 和持续症状 (PS) 组.
- 在ER和PS组之间比较人口,临床和症状概况.
主要成果:
- 持久性症状组的女性患者比例较高 (59.4%对47.3%).
- 在PS组的女性患者报告了更多的疲劳,失眠,记忆问题和麻醉症.
- 患有超过三个初始症状的患者在PS组中更常见,疲劳和抑郁症得分更高.
结论:
- 长时间的COVID持续时间与最初症状的数量有关.
- 性别特定的症状模式和较高的症状负担与持续的长期COVID相关.
- 这些发现突显了长期COVID轨迹中的性别依赖差异.
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