风湿病学家对EULAR系统性硬化症治疗建议的遵守:塞尔维亚单一中心的经验
Slavica Pavlov-Dolijanovic1, Ivan Jeremic2, Milan Bogojevic3
1Faculty of Medicine, Institute of Rheumatology, University of Belgrade, 11000 Belgrade, Serbia.
Journal of clinical medicine
|July 29, 2025
概括
风湿病学家 风湿病学家
科学领域:
- 类风湿病学 类风湿病学
- 临床药理学 临床药理学
背景情况:
- 2009年由EULAR/EUSTAR发布的第一个系统性硬化症 (SSc) 治疗指南,于2016年和2023年更新.
- 评估类风湿病学家治疗方法的演变2016年后的SSc指南更新.
研究的目的:
- 在2016年EULAR/EUSTAR指导方针之后,评估SSc治疗策略的变化.
- 在指南更新之前和之后,分析SSc患者的药物使用模式.
主要方法:
- 对378名SSc患者药物使用的回顾性分析.
- 根据2016年指南更新之前 (233) 和之后 (145) 的入学情况进行患者分层.
- 两个队列之间的药物处方模式的比较.
主要成果:
- 对雷诺现象 (RP) 和数字的推治疗方法的吸收率低.
- 增加了分别用于PAH和ILD的固酶5型 (PDE-5) 抑制剂和循环胺后指南更新的使用.
- 持续使用质子抑制剂 (PPI) 和用于胃肠道干扰的 prokinetic 药物,在 2016 年后使用率增加.
结论:
- 不同类型的风湿病学家遵守EULAR/EUSTAR SSc指南 (25%-100%).
- 在管理肺动脉高血压 (PAH),间歇性肺病 (ILD) 和胃肠道问题的2016年后更新后改善一致性.
- 需要加强指导方针的实施和监测在SSC护理.
相关概念视频
01:21Rheumatic Heart Disease III: Medical Management
32
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
32
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
59
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
59
01:20Rheumatic Heart Disease IV: Nursing Management
38
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
38
01:23Rheumatic Heart Disease I: Introduction
43
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
43
01:22Connective Tissue Cell Types
3.4K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.4K
01:26Nephrotic Syndrome II : Assessment and Medical Management
23
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
23