布鲁克斯症和阻塞性睡眠呼吸暂停之间的关系:对文献的系统审查
Natalia García Doblado1, José María Barrera Mora2, Francisco Pastor Dorado2
1School of Dentistry, University of Sevilla, 41009 Sevilla, Spain.
Journal of clinical medicine
|July 29, 2025
概括
睡眠呼吸障碍症 (OSA) 患者中睡眠呼吸障碍症 (SB) 的患病率更高,这表明有共同的机制. 需要进一步的标准化研究来证实睡眠呼吸障碍和睡眠呼吸暂停之间的联系.
科学领域:
- 睡眠医学 睡眠医学
- 神经学 神经学
- 口腔健康 口腔健康
背景情况:
- 越来越多的人对布鲁克斯症和睡眠呼吸暂停之间的联系越来越感兴趣,因为它们对健康有重大影响.
- Bruxism 影响 8-31% 的人口; 阻塞性睡眠呼吸暂停 (OSA) 影响 4-6% 的男性和 2-4% 的女性,影响生活质量和增加健康风险.
- 睡眠 Bruxism (SB) 和OSA之间的因果关系仍然不清楚.
研究的目的:
- 系统地审查现有证据,以了解睡眠 (SB) 和阻塞性睡眠呼吸暂停 (OSA) 之间的关联.
- 确定潜在的共同风险因素和连接SB和OSA的潜在病理生理机制.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science,Cochrane Library) 中进行电子文献搜索,查找2020年至2025年间发表的研究.
- 包括观察性研究和临床试验,涉及SB和/或OSA的成年人.
- 使用ROBINS-I评估偏差风险和使用GRADE的证据确定性.
主要成果:
- 十一项研究符合纳入标准,表明在患有OSA的个体中,SB的流行率始终较高.
- 建议的潜在联系包括自主性兴奋和神经递质失调.
- 由于诊断标准的不一致性和方法质量中等,研究结果受到限制.
结论:
- 在OSA患者中存在显著的布鲁克斯症患病率,这表明可能存在共享的病理生理机制.
- 标准化诊断标准和进行更大,更强大的研究是必要的,以澄清SB-OSA关系.
- 没有收到任何资金,也没有宣布任何利益冲突.
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