关于管理牛皮关节炎的APLAR建议
Ying-Ying Leung1,2, Paul Bird3, Muhammad Haroon4
1Department of Rheumatology, Singapore General Hospital, Singapore, Singapore.
International journal of rheumatic diseases
|July 29, 2025
概括
为亚太地区的牛皮关节炎 (PsA) 管理制定了新的指导方针. 这些基于证据的建议有助于卫生专业人员有效治疗PSA患者.
科学领域:
- 类风湿病学 类风湿病学
- 皮肤病学 皮肤病学
- 临床实践指南 临床实践指南
背景情况:
- 牛皮关节炎 (PsA) 管理需要特定区域的,基于证据的指导方针.
- 亚太风湿病学协会联盟 (APLAR) 发起了这些指南的制定.
研究的目的:
- 制定全面的,基于证据和共识的指导方针,用于管理亚太地区的牛皮关节炎 (PsA).
- 为医疗专业人员提供最佳PSA患者护理建议.
主要方法:
- 召集了来自18个APLAR国家的35名专家 (风湿病学家,皮肤病学家,患者合作伙伴) 的工作组.
- 使用GRADE方法对治疗剂的疗效和安全进行了系统的文献审查.
- 通过工作组和外部投票小组 (n=90) 制定了建议声明,并通过工作组和外部投票小组达成共识.
主要成果:
- 审查了178篇关于PsA的临床试验文章以及有关并发症和感染的额外文献.
- 为PSA制定了八项管理原则和16项建议声明.
- 获得了外部投票小组的强烈支持,回复率为80%.
结论:
- 这些代表了APLAR第一个针对牛皮关节炎管理的区域具体建议.
- 准则将最好的可用证据与特定区域的考虑结合起来.
- 通过多学科合作和专家共识开发.
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