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Updated: Sep 13, 2025

Identifying Microglia and Peripheral Infiltrating Macrophages in the Injured Spinal Cords Using Flow Cytometry
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转录基因剖析揭示了感官神经元微环境中外围质细胞的损伤反应

Jiacheng Xu1,2, Jiaxin Jin3, Saizhen Lv4

  • 1Suzhou Medical College of Soochow University, Suzhou, China.

Journal of neuroscience research
|July 29, 2025
PubMed
概括

外围质细胞,包括施万细胞和卫星质细胞 (SGCs),在坐骨神经受伤后显示出明显的转录变化. 激活因子3 (Atf3) 在所有质细胞上升调节,为神经再生提供了洞察力.

关键词:
施万的细胞是斯万的细胞.生物信息分析分析生物信息分析背部根部的角质组织.肌化 肌化 肌化非髓化的非髓化卫星状细胞 卫星状细胞

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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