在正常怀孕中,使用卓越的微血管成像,对静脉动脉小动脉的纵向评估
R Horgan1, E Sinkovskaya1, G Saade1,2
1Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Macon & Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, VA, USA.
概括
优秀的微血管成像 (SMI) 允许在整个怀孕期间可视化胎盘血流在静脉动脉 (IVA) 中的血流. 这项研究建立了IVA脉动性指数 (PI) 和从怀孕12周到38周的峰值缩速度 (PSV) 的参考范围.
科学领域:
- 产科和妇科 产科和妇科
- 胎儿医学 胎儿医学
- 医疗成像医学成像
背景情况:
- 胎盘血管发育对于健康的怀孕至关重要.
- 评估胎盘微血管中的血液流动,可以了解胎儿的健康状况.
- 血管内动脉小动脉 (IVA) 血流的长度评估是有限的.
研究的目的:
- 用超级微血管成像 (SMI) 纵向评估静脉动脉 (IVA) 中的血流.
- 在怀孕期间 (12-38周妊娠期) 制定IVA脉动性指数 (PI) 和缩速度峰值 (PSV) 的参考范围.
主要方法:
- 一项前性研究包括90名没有并发症的单胎妊娠的妇女.
- 超级微血管成像 (SMI) 用于评估每个参与者的6个IVA中的血流.
- 使用多级回归模型来确定IVA-PI和IVA-PSV的参考范围.
主要成果:
- 静脉动脉脉动指数 (IVA-PI) 从第一季度的1.04 ± 0.23下降到第三季度末的0.75 ± 0.10.
- 静脉动脉峰缩速度 (IVA-PSV) 从12-13周的5.97 ± 1.47厘米/秒增加到第三个月末的约13.09 ± 4.64厘米/秒的平原.
- 对IVA-PI和IVA-PSV的参考范围已成功开发为妊娠12-38周.
结论:
- 优秀的微血管成像 (SMI) 能够可靠地可视化和量化胎盘静脉动脉 (IVA) 血流.
- 确定的参考范围为监测正常妊娠进展提供了有价值的工具.
- 这种技术具有早期检测胎盘血管异常的潜力.
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