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Updated: Sep 13, 2025

Author Spotlight: Uncovering the Role of Mitochondrial Calcium Phosphate in Heart Failure and Bioenergetics
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SLC39A13通过维护线粒体铁平衡维持心脏功能的调节

Huihui Li1, Xiaoting Wang2, Yu Zhang1

  • 1Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China (H.L., Y.Z.).

Circulation research
|July 29, 2025
PubMed
概括

溶解体载体家族39成员13 (SLC39A13) /ZIP13缺乏通过破坏线粒体铁平衡导致严重的心脏功能障碍. 恢复心肌细胞中的线粒体铁平衡可以改善心脏功能,突出显示ZIP13的关键作用.

关键词:
恒常状态 (homeostasis) 是一种平衡状态.铁是铁,铁是铁,铁是铁.鼠标 鼠标 鼠标 鼠标线粒体中的线粒体.肌细胞,心脏细胞.

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